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Table 4 Association of knee pain stratified by knee synovial abnormalities on ultrasound and radiographic osteoarthritis status

From: Prevalence of ultrasound-detected knee synovial abnormalities in a middle-aged and older general population—the Xiangya Osteoarthritis Study

Synovial abnormalities and ROA status

No. of patients with knee pain (%)

Crude OR (95% CI)a

Adjusted OR (95% CI)a

P value of interaction

Synovial hypertrophy

   

0.004

 Neither synovial hypertrophy nor ROA

1013 (20.6)

1.00 (reference)

1.00 (reference)

 

 Synovial hypertrophy only

86 (25.4)

1.31 (1.00, 1.71)

1.46 (1.10, 1.93)

 

 ROA only

772 (47.7)

3.51 (3.04, 4.04)

2.45 (2.10, 2.87)

 

 Synovial hypertrophy and ROA

313 (65.8)

7.40 (5.86, 9.34)

5.51 (4.27, 7.11)

 

Joint effusion

   

0.067

 Neither joint effusion nor ROA

744 (19.7)

1.00 (reference)

1.00 (reference)

 

 Joint effusion only

355 (24.1)

1.29 (1.10, 1.52)

1.34 (1.13, 1.59)

 

 ROA only

560 (47.8)

3.74 (3.17, 4.40)

2.62 (2.18, 3.14)

 

 Joint effusion and ROA

525 (56.8)

5.35 (4.47, 6.40)

3.86 (3.18, 4.69)

 

Power Doppler signal

   

0.794

 Neither Power Doppler signal nor ROA

1075 (20.7)

1.00 (reference)

1.00 (reference)

 

 Power Doppler signal only

24 (45.3)

3.18 (1.81, 5.58)

3.12 (1.70, 5.73)

 

 ROA only

971 (50.0)

3.84 (3.35, 4.39)

2.69 (2.31, 3.12)

 

 Power Doppler signal and ROA

114 (74.0)

10.94 (7.34, 16.30)

8.34 (5.44, 12.80)

 
  1. OR odds ratio, CI confidence interval, ROA radiographic osteoarthritis
  2. aAdjusted for age, sex, BMI, smoking status, alcohol consumption, education level, and knee injury history