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Table 1 Demographics, cardiovascular risk factors, and disease-related data in RA patients

From: Disease activity influences the reclassification of rheumatoid arthritis into very high cardiovascular risk

  RA (n = 1279)
Age, years 58 ± 13
Female, n (%) 982 (72)
BMI, kg/m2 28 ± 5
Abdominal circumference, cm 94 ± 15
Cardiovascular data
 CV risk factors, n (%)
  Current smoker 326 (25)
  Obesity 354 (28)
  Dyslipidemia 611 (48)
  Hypertension 468 (37)
  Diabetes mellitus 0 (0)
 Blood pressure, mmHg
  Systolic 131 ± 17
  Diastolic 78 ± 10
 Lipids
  Total cholesterol, mmol/l 5.28 ± 0.96
  Triglycerides, mmol/l 1.27 ± 0.70
  HDL cholesterol, mmol/l 1.58 ± 0.44
  LDL cholesterol, mmol/l 3.10 ± 0.80
  Atherogenic index 3.56 ± 1.06
 Statins, n (%) 303 (24)
 Aspirin, n (%) 43 (3)
 Antihypertensive treatment, n (%) 335 (26)
Disease-related data
 Disease duration, years 5 (2–12)
 CRP at time of study, mg/l 2.7 (0.9–6.7)
 ESR at time of study, mm/1° h 12 (5–23)
 Rheumatoid factor, n (%) 753 (59)
 ACPA, n (%) 682 (53)
 DAS28-ESR 3.09 ± 1.49
 DAS28-PCR 2.99 ± 1.28
 SDAI 10 (5–18)
 CDAI 9 (4–16)
 HAQ 0.750 (0.250–1.250)
 RAPID 3.15 ± 2.03
 Current drugs, n (%)
  Prednisone 636 (50)
  Prednisone doses, mg/day 5 (4–6)
  NSAIDs 498 (39)
  DMARDs 983 (77)
  Methotrexate 730 (57)
  Leflunomide 141 (11)
  Hydroxychloroquine 282 (22)
  Sulphasalazine 44 (3)
  Anti-TNF therapy 166 (13)
   Adalimumab 56 (4)
   Infliximab 18 (1)
   Etanercept 66 (5)
   Golimumab 5 (0)
  Tocilizumab 65 (5)
  Rituximab 21 (2)
  Abatacept 22 (2)
  Baricitinib 12 (1)
  Tofacitinib 14 (1)
Historical disease-related data
 History of extraarticular manifestations, n (%) 232 (18)
 Erosions, n (%) 453 (35)
 CRP at time of disease diagnosis, mg/l 7.0 (2.0–20.0)
 CRP > 3 at time of diagnosis, n (%) 685 (54)
 ESR at the time of disease diagnosis, mm/1° h 21 (11.38)
 Subclinical atherosclerosis
  Carotid IMT, μm 690 ± 140
  Carotid plaques, n (%) 678 (53)
  1. Data represent means ± SD or median (IQR) when data were not normally distributed
  2. CV cardiovascular, LDL low-density lipoprotein, HDL high-density lipoprotein, CRP C-reactive protein, NSAID nonsteroidal anti-inflammatory drugs, DMARD disease-modifying antirheumatic drug, TNF tumor necrosis factor, Obesity, ESR erythrocyte sedimentation rate, BMI body mass index, DAS28 Disease Activity Score in 28 joints, ACPA anti-citrullinated protein antibodies, RAPID routine assessment of patient index, CDAI Clinical Disease Activity Index, SDAI Simple Disease Activity Index, HAQ Health Assessment Questionnaire