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Table 1 Baseline characteristics of the study population

From: Tumour necrosis factor inhibitors reduce aortic stiffness progression in patients with long-standing rheumatoid arthritis

Variables

csDMARDs (n=43)

TNFi (n=64)

P-value

Cardiovascular disease risk factors

 Age, median years (IQR)

58.6 (53.0, 66.0)

58.1 (49.3, 67.0)

0.839

 Female sex

33 (76.7)

54 (84.4)

0.321

 Obesity

5 (11.6)

7 (10.9)

0.999

 Hypertension

19 (44.2)

30 (46.9)

0.784

 Anti-hypertensive drug

17 (39.5)

28 (43.8)

0.784

 Smoking status, ever

18 (42.9)

30 (46.9)

0.684

 Dyslipidaemia

30 (40.2)

34 (59.8)

0.085

 Current statin use

13 (34.2)

10 (15.9)

0.033

 Diabetes mellitus

3 (7.0)

3 (4.7)

0.676

 Anti-diabetic medication

1 (2.3)

1 (1.5)

0.999

 CVD risk factors, median (IQR)

2 (1, 3)

2 (1, 3)

0.199

Rheumatoid arthritis characteristics and treatment

 RF and/or ACPA positive

28 (65.1)

33 (51.6)

0.165

 Disease duration, median years (IQR)

14.1 (11.5)

15.4 (10.5)

0.538

 Methotrexate

38 (88.4)

52 (81.3)

0.192

 Leflunomide

5 (17.9)

12 (19.0)

0.999

 Hydroxychloroquine

9 (31.0)

5 (7.8)

0.009

 Prednisone > 5 mg daily

7 (7.7)

5 (5.5)

0.823

 NSAIDs

6 (20.7)

22 (34.4)

0.227

  1. ACPA, anti-citrullinated peptides antibodies; csDMARDs, conventional synthetic disease-modifying anti-rheumatic drugs; IQR, interquartile range; NSAIDs, non-steroidal anti-inflammatory drugs; RF, rheumatoid factor; TNFi, tumour necrosis factor inhibitors. All data reported as absolute numbers (percentage) otherwise specified. P-value refers to the chi-squared or Fisher test for categorical variables or independent samples T-test for continuous variables