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Table 3 Immunomodulatory therapies among all PRESS participants at any time during the course of the study

From: Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort

Treatments (n = 301)

Baseline only

Any time during study*

Mycophenolate mofetil, n (%)

121 (40.2)

207 (68.8)

 Dose (mg/day), mean (±SD)

1876.9 (±737.0)

2045.4 (±644.5)

Methotrexate, n (%)

42 (14.0)

64 (21.3)

 Dose (mg/week), mean (±SD)

14.9 (±6.8)

15.8 (±5.6)

Cyclophosphamide, n (%)

6 (2.0)

15 (5.0)

 Dose (mg/day), mean (±SD)

33.6 (±14.4)

44.4 (±27.0)

D-penicillamine, n (%)

5 (1.7)

8 (2.7)

 Dose (mg/day), mean (±SD)

650.0 (±285.0)

686.9 (±246.6)

Hydroxychloroquine, n (%)

39 (13.0)

53 (17.6)

 Dose (mg/day), mean (±SD)

319.4 (±103.7)

317.8 (±97.1)

Azathioprine, n (%)

5 (1.7)

7 (2.3)

 Dose (mg/day), mean (±SD)

115.0 (±41.8)

110.7 (±34.9)

Any immunomodulatory therapy, n (%)

190 (63.1)

260 (86.4)

Autologous hematopoietic stem cell transplantation, n (%)

1 (0.3)

4 (1.3)

Prednisone, n (%)

90 (29.9)

127 (42.2)

 Dose (mg/day), mean (±SD)

9.9 (±7.9)

9.2 (±5.2)

  1. *Any time: including all patients with this medication any time during follow-up and/or at baseline