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Table 4 Cumulative incidence of events after years of follow-up among all PRESS participants

From: Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort

Outcomes

0–1 year

0–2 years

0–3 years

Overall mortality

11/301 (3.7%)

16/301 (5.3%)

18/301 (6.0%)

mRSS worsening1,*

43/216 (19.9%)

45/224 (20.1%)

46/227 (20.3%)

FVC worsening2,**

21/165 (12.7%)

32/175 (18.3%)

36/176 (20.5%)

  1. mRSS, modified Rodnan skin score; FVC, forced vital capacity
  2. 1Choice of denominator: participants who had baseline mRSS and at least one follow-up mRSS up to n years (where n = 1, 2, or 3) were included in the denominator
  3. 2Choice of denominator: participants who had baseline FVC% and at least one follow-up FVC% up to n years (where n = 1, 2, or 3) were included in the denominator
  4. *Clinically significant worsening of skin disease was defined as an absolute increase of mRSS ≥ 5 units or ≥ 25% as compared to baseline mRSS
  5. **Significant functional progression of ILD was defined as an absolute FVC decline of ≥ 10% as compared to baseline FVC
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Arthritis Research & Therapy

ISSN: 1478-6362

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