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Table 1 AAU Flare reported in the included RCTs

From: Incidence of anterior uveitis in patients with axial spondyloarthritis treated with anti-TNF or anti-IL17A: a systematic review, a pairwise and network meta-analysis of randomized controlled trials

Study (ref) Treatment Placebo
  Treatment Study duration (weeks) Patients (n) Uveitis (n) Incidence (per 100 PY) Patients (n) Uveitis (n) Incidence (per 100 PY)
Van der Heijde D et al. 2006 [23] ADA 24 208 0 0.00 107 0 0.00
Sieper J et al. 2012 [24] ADA 12 95 0 0.00 97 0 0.00
Huang F et al. 2013 [25] ADA 12 229 0 0.00 115 0 0.00
Landewé R et al. 2013 [27] CTZ 24 218 2 1.98 107 3 6.07
Deodhar A et al. 2019 [28] CTZ 52 159 4 2.51 158 8 5.06
Inman R et al. 2008 [29] GOL 24 278 0 0.00 77 0 0.00
Deodhar A et al. 2017 [32] GOL 16 105 0 0.00 103 2 6.31
Sieper J et al. 2015 [31] GOL 16 97 0 0.00 100 0 0.00
Bao C et al. 2014 [30] GOL 24 169 1 1.28 44 0 0.00
Van der Heijde D et al. 2005 [34] IFX 18 202 0 0.00 75 0 0.00
Barkham N et al. 2009 [36] IFX 16 20 0 0.00 20 0 0.00
Inman R et al. 2010 [37] IFX 12 39 0 0.00 37 0 0.00
Marzo-Ortega H et al. 2005 [35] IFX 30 28 1 6.19 14 0 0.00
Sieper J et al. 2012 [38] IFX 28 105 0 0.00 52 0 0.00
Braun J et al. 2002 [33] IFX 12 34 1 12.74 35 3 37.14
Gorman JD et al. 2002 [40] ETN 16 20 0 0.00 20 0 0.00
Davis JC et al. 2003 [41] ETN 24 138 3 4.71 139 8 12.47
Brandt J et al. 2003 [42] ETN 6 14 0 0.00 16 0 0.00
Calin A et al. 2004 [43] ETN 12 45 0 0.00 39 0 0.00
Van der Heijde D et al. 2006 [44] ETN 12 305 0 0.00 51 1 8.49
Barkham N et al. 2010 [45] ETN 12 15 0 0.00 17 0 0.00
Dougados M et al. 2011 [46] ETN 12 39 0 0.00 43 0 0.00
Dougados M et al. 2014 [48] ETN 8 42 0 0.00 48 0 0.00
Dougados M et al. 2014 [47] ETN 12 106 0 0.00 109 0 0.00
Deodhar A et al. 2019 [54] IXE 16 212 5 7.66 104 0 0.00
Van der Heijde D et al. 2018 [26] IXE 16 164 1 1.98 86 0 0.00
Deodhar A et al. 2019 [55] IXE 52 198 3 2.09 104 2 1.92
Baeten D et al. 2013 [49] SEC 28 24 0 0.00 6 0 0.00
Baeten D et al. 2015 [50] SEC 16 394 7 5.77 196 2 3.31
Pavelka K et al. 2017 [51] SEC 16 150 0 0.00 75 0 0.00
Kivitz A et al. 2018 [52] SEC 16 233 0 0.00 117 0 0.00
Deodhar A et al. 2019 [53] SEC 52 369 7 1.21 186 2 1.07
Giardina A et al. 2010 [39] IFX 104 25 1 2.00 - - -
ETN 25 2 4.00 - - -