Predictors of unacceptable pain with and without low inflammation over 5 years in early rheumatoid arthritis—an inception cohort study

Table 5 Baseline predictors of unacceptable pain with low inflammation in early RA, multivariate analysis

Variable	Odds ratio	95% CI	P value
1 year after inclusion
VAS pain	1.62	1.11–2.39	0.01
ESR	0.54	0.33–0.88	0.01
Age	0.72	0.51–1.01	0.06
2 years after inclusion
Female sex	2.41	0.93–6.23	0.07
Age	0.71	0.50–0.99	0.04
Erosion	0.30	0.07–1.38	0.12
CRP < 9 mg/l	1.00 (reference)	-	-
CRP 9–27.4 mg/l	0.91	0.39–2.17	0.84
CRP ≥ 27.5 mg/l	0.49	0.17–1.42	0.19
5 years after inlcusion
Anti-CCP seropositivity	0.43	0.20–0.95	0.04
SJC28	0.63	0.39–1.00	0.05
PGA	1.51	1.01–2.25	0.04

Legend: Multivariate logistic regression analysis. Odds ratios are calculated per standard deviation for continuous variables. Unacceptable pain: VAS pain > 40. Low inflammation: CRP < 10 mg/l. CI confidence interval, VAS visual analogue scale, ESR erythrocyte sedimentation rate, CRP C-reactive protein, Anti-CCP anti-cyclic citrullinated peptide, SJC28 swollen joint count in 28 joint, PGA patient global assessment