Skip to main content

Table 6 Baseline predictors of VAS pain over time (from inclusion to 5 years) in early RA

From: Predictors of unacceptable pain with and without low inflammation over 5 years in early rheumatoid arthritis—an inception cohort study

Variable

Estimated mean difference at baseline per SD (95% CI)

Estimated mean difference over time per SD (95% CI)

Difference in change/month per SD (95% CI)

RF seropositivity

3.03 (− 2.31, 8.37)

3.27 (− 1.51, 8.04)

0.01 (− 0.12, 0.15)

Anti-CCP seropositivity

2.99 (− 2.73, 8.71)

2.37 (− 2.78, 7.52)

− 0.03 (− 0.17, 0.10)

HAQ

9.74 (7.32, 12.16)

7.37 (5.24, 9.50)

− 0.13 (− 0.19, − 0.07)

VAS PGA

11.19 (8.85, 13.52)

8.88 (6.85, 10.91)

− 0.13 (− 0.19, − 0.06)

Grip force

− 5.94 (− 8.69, − 3.19)

− 4.64 (− 7.11, − 2.18)

0.07 (0, 0.13)

DAS28

9.62 (7.18, 12.06)

6.80 (4.65, 8.96)

− 0.15 (− 0.22, − 0.09)

SJC28

3.44 (0.85, 6.03)

1.11 (− 1.21, 3.43)

− 0.12 (− 0.19, − 0.06)

TJC28

5.97 (3.42, 8.52)

3.96 (1.69, 6.23)

− 0.11 (− 0.18, − 0.05)

ESR

4.40 (1.82, 6.98)

2.66 (0.35, 4.97)

− 0.10 (− 0.16, − 0.03)

CRP

4.36 (1.80, 6.92)

2.29 (0, 4.58)

− 0.11 (− 0.17, − 0.05)

Age

− 4.48 (− 7.06, − 1.90)

− 3.08 (− 5.38, − 0.78)

0.08 (0.01, 0.14)

  1. Legend: Mixed model analysis, using all VAS pain values at inclusion and at follow-ups after 6 months and 1, 2 and 5 years. SD standard deviation, CI confidence interval, RF rheumatoid factor, Anti-CCP anti-cyclic citrullinated peptide, HAQ health assessment questionnaire, VAS visual analogue scale, PGA patient global assessment, DAS28 disease activity score in 28 joints, SJC28 swollen joint count in 28 joints, TJC28 tender joint count in 28 joints, ESR erythrocyte sedimentation rate, CRP C-reactive protein