Table 3 Comparison of NVC alterations between APS and "aPL carriers" and between APS and CTR group
From: Antiphospholipid antibodies and anticoagulant therapy: capillaroscopic findings
VCP evaluation | APS | "aPL carriers" | p-value | CTR | p-value |
|---|---|---|---|---|---|
Global pattern (%) | |||||
Normal | 3 (16.7) | 8 (33.3) | 0.299 | 7 (38.9) | 0.264 |
Non-specific alterations | 15 (83.3) | 16 (66.7) | 0.299 | 11 (61.1) | 0.264 |
AB score, median [IQR] | |||||
A-score | 2.0 [2.0, 3.0] | 1.0 [1.0, 2.0] | 0.004 | 1.5 [1.0, 2.0] | 0.021 |
B-score | 0.0 [0.0, 0.8] | 0.0 [0.0, 0.0] | 0.098 | 0.0 [0.0, 0.0] | 0.674 |
Dilated capillaries | |||||
Median score [IQR] | 1.0 [1.0, 2.0] | 1.0 [1.0, 1.0] | 0.009 | 1.0 [1.0, 1.0] | 0.027 |
Number of patients (%) | 17 (94.4) | 20 (83.3) | 0.536 | 18 (100.0) | 1 |
Giant capillaries | |||||
Number of patients (%) | 0 (0.0) | 0 (0.0) | – | 0 (0.0) | – |
Microhemorrhages | |||||
Median score [IQR] | 1.0 [0.0, 1.0] | 0.0 [0.0, 1.0] | 0.034 | 0.0 [0.0, 1.0] | 0.186 |
Number of patients (%) | 12 (66.7) | 8 (33.3) | 0.032 | 8 (44.4) | 0.314 |
Abnormal shapes | |||||
No. of patients (%) | 2 (11.1) | 0 (0.0) | 0.178 | 2 (11.1) | 1 |
Reduced numerosity | |||||
No. of patients (%) | 1 (5.6) | 0 (0.0) | 0.429 | 0 (0.0) | 1 |
Absolute value of capillaries, median [IQR] | 9.5 [9.0, 10.0] | 10.0 [9.0, 10.0] | 0.946 | 10.5 [10.0, 11.8] | 0.010 |
Single hemorrhages | |||||
Median [IQR] | 0.0 [0.0, 0.8] | 0.0 [0.0, 0.2] | 0.767 | 0.0 [0.0, 1.0] | 0.461 |
No. of patients (%) | 5 (27.8) | 6 (25.0) | 0.875 | 7 (38.9) | 0.72 |
“Comb-like” hemorrhages | |||||
Median [IQR] | 0.5 [0.0, 1.0] | 0.0 [0.0, 0.0] | 0.007 | 0.0 [0.0, 0.0] | 0.029 |
No. of patients (%) | 8 (50) | 3 (12.5) | 0.020 | 3 (16.7) | 0.034 |