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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Guselkumab demonstrated an independent treatment effect in reducing fatigue after adjustment for clinical response—results from two phase 3 clinical trials of 1120 patients with active psoriatic arthritis

Fig. 1

Mediation analysis. Direct effect = treatment effect on outcome independent of the effect on the mediator; indirect effect = treatment effect on outcome that is attributed to its effect on the mediator. ACR20, ≥20% improvement in American College of Rheumatology criteria

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