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Table 3 Correlation between TBS and GC cumulative dose with different serum bone markers in the whole group of patients, in the lGC group and hGC group

From: Influence of glucocorticoid treatment on trabecular bone score and bone remodeling regulators in early rheumatoid arthritis

 

All patients (N = 47)

Low GC group (N = 22)

High GC group

Variable

TBS

Cumulative GC dose

TBS

Cumulative GC dose

TBS

Cumulative GC dose

TBS

–

 

–

 

–

 

Cumulative dose GC

− 0.19 (ns)

–

0.003 (ns)

–

− 0.4 (p = 0.048)

–

DKK

− 0.86 (p < 0.0001)

0.12(ns)

− 0.82 (p < 0.0001)

0.62

− 0.9 (p < 0.0001)

0.42 (p = 0.033)

Sclerostin

− 0.43 (p = 0.003)

0.32 (p = 0.026)

− 0.58 (p = 0.004)

0.07 (ns)

− 0.47 (p = 0.04)

0.16 (ns)

RANK-L

− 0.76 (p < 0.001)

0.14 (ns)

− 0.75 (p < 0.0001)

0.54 (ns)

− 0.71 (p < 0.0001)

0.22 (ns)

OPG

0.43 (p = 0.002)

− 0.37 (p = 0.009)

0.38 (ns)

− 0.9 (ns)

0.45 (p = 0.023)

− 0.33 (ns)

OPG/RANK-L

0.76 (p < 0.0001)

− 0.23 (ns)

0.78 (p < 0.0001)

− 0.11 (ns

0.74 (p < 0.0001)

− 0.32 (ns)