Ingenuity canonical pathways | – log (p value) | Ratio (genes/total genes) | Positively associated genes | Negatively associated genes |
---|---|---|---|---|
DNA methylation and transcriptional repression signaling | 2.18 | 7/33 | CHD4,MTA2,SIN3A | DNMT3A,DNMT3B,H4C14,MBD2 |
tRNA splicing | 2.06 | 8/43 | PDE1C,PDE4B,PDE5A,PDE8A | MPPED2,PDE1A,PDE7A,SMPDL3B |
Regulation of the epithelial mesenchymal transition in development pathway | 1.96 | 12/82 | AXIN1,GLI2,GLI3,JAG2,TCF4,WNT11,WNT8B, WNT9A | RBPJ,SNAI2,WNT3A,WNT5B |
Sphingosine and sphingosine-1-phosphate metabolism | 1.84 | 3/8 | ACER3 | ASAH1,SGPP1 |
TCA cycle II (eukaryotic) | 1.65 | 5/24 | IDH3B,IDH3G | DLD,MDH1B,SUCLA2 |
Branched-chain α-keto acid dehydrogenase complex*# | 1.58 | 2/4 | BCKDHB | DLD |
Molybdenum cofactor biosynthesis | 1.58 | 2/4 | Â | MOCS3,NFS1 |
D-myo-inositol (1,4,5)-trisphosphate biosynthesis | 1.57 | 5/25 | PI4KA,PIP4K2A,PIP5K1B | PI4K2A,PIP4K2B |
Assembly of RNA polymerase I complex | 1.44 | 3/11 | Â | POLR1B,TAF1A,TAF1C |