Table 4 Risk of damage accrual by HDAS episode duration
From: Disease course following High Disease Activity Status revealed patterns in SLE
HDAS episode duration | Odds of accruing damage | |||
|---|---|---|---|---|
Unadjusted | Adjusted for observation timea | |||
OR (95% CI) | p value | OR (95% CI) | p value | |
Never experienced HDAS | 1 | Not applicable | 1 | Not applicable |
Cumulative HDAS duration | ||||
≥1 day and < 1 year | 1.64 (0.90–2.97) | 0.12 | 1.48 (0.49–4.08) | 0.46 |
≥1 year and < 2 years | 1.70 (0.76–3.83) | 0.19 | 1.27 (0.60–2.39) | 0.49 |
2 years or more | 5.55 (2.88–10.71) | < 0.001* | 1.80 (1.08–2.97) | 0.02* |
Mean duration of HDAS episode | ||||
≥1 day and < 1 year | 2.31 (1.41–3.81) | < 0.001* | 2.12 (0.88–5.00) | 0.09 |
≥1 year and < 2 years | 1.81 (0.71–4.62) | 0.30 | 0.93 (0.27–2.31) | 0.88 |
2 years or more | 6.37 (2.30–17.66) | < 0.001* | 1.60 (0.91–2.67) | 0.08 |