Skip to main content

Table 4 Risk of damage accrual by HDAS episode duration

From: Disease course following High Disease Activity Status revealed patterns in SLE

HDAS episode duration Odds of accruing damage
Unadjusted Adjusted for observation timea
OR (95% CI) p value OR (95% CI) p value
Never experienced HDAS 1 Not applicable 1 Not applicable
Cumulative HDAS duration
 ≥1 day and < 1 year 1.64 (0.90–2.97) 0.12 1.48 (0.49–4.08) 0.46
 ≥1 year and < 2 years 1.70 (0.76–3.83) 0.19 1.27 (0.60–2.39) 0.49
 2 years or more 5.55 (2.88–10.71) < 0.001* 1.80 (1.08–2.97) 0.02*
Mean duration of HDAS episode
 ≥1 day and < 1 year 2.31 (1.41–3.81) < 0.001* 2.12 (0.88–5.00) 0.09
 ≥1 year and < 2 years 1.81 (0.71–4.62) 0.30 0.93 (0.27–2.31) 0.88
 2 years or more 6.37 (2.30–17.66) < 0.001* 1.60 (0.91–2.67) 0.08
  1. OR odds ratio, CI confidence interval
  2. *Statistically significant at p < 0.05
  3. aAdjusted for observation time modelled as a categorical variable (< 5 years, 5–< 10 years, and 10+ years)