Disease course following High Disease Activity Status revealed patterns in SLE

Table 5 Risk of damage accrual by number of HDAS episodes

Number of HDAS episodes	Odds of accruing damage
	Unadjusted		Adjusted for observation time^a
	OR (95% CI)	p value	OR (95% CI)	p value
0	1	Not applicable	1	Not applicable
1	1.35 (0.72–2.51)	0.41	1.74 (0.63–4.5)	0.27
2	2.27 (1.13–4.55)	0.02*	1.09 (0.48–2.15)	0.83
3	2.23 (0.92–5.41)	0.08	1.44 (0.74–2.58)	0.23
4 or more	20.29 (5.80–70.98)	<0.001*	3.31 (1.66–13.26)	0.01*

OR odds ratio, CI confidence interval
*Statistically significant at p < 0.05
^aAdjusted for observation time modelled as a categorical variable (<5 years, 5–<10 years, and 10+ years)

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