Fig. 2

Oxylipin profile is different in PsA patients by skin disease activity. A PLS-DA scores plot of PsA patients with higher (N = 6) versus lower PASI (N = 13). The explained variances for each component are shown in brackets. B Important features identified by PLS-DA. The colored boxes on the right indicate the relative concentrations of the corresponding metabolite in each group under study. C Heatmap performed using the important features identified by PLS-DA which shows different patterns in the 2 groups. D Precursor assignment for the oxylipins that are decreased (blue rectangle) in PsA patients with higher disease activity compared to the lower group. Oxylipins that are increased in PsA patients with higher disease activity are marked in a red rectangle