Fig. 3

Surface expression of CCR4, CCR6, and CXCR3 on human T cell functional subset. A, B Representative plots and statistical data of CD4+T cell and CD8+T cell subsets. CD4+T cell subsets and CD8+ T cells subsets from the peripheral blood were identified according to the expression of CCR7 and CD45RO. The percentage of Tnaïve (CCR7+CD45RO−), TCM (CCR7+CD45RO+), TEM (CCR7-CD45RO+), and TEMRA (CCR7−CD45RO−) in the peripheral blood of HC and active MPO-AAV patients is shown (n MPO-AAV=33, HC=20). C, D Percentages of CCR6+ T cells, CCR4+ T cells CXCR3+ T cells in the TEM (CCR7−CD45RO+), and TEMRA (CCR7−CD45RO−) subpopulation were shown