Fig. 3

Surface expression of CCR4, CCR6, and CXCR3 on human T cell functional subset. A, B Representative plots and statistical data of CD4⁺T cell and CD8⁺T cell subsets. CD4⁺T cell subsets and CD8⁺ T cells subsets from the peripheral blood were identified according to the expression of CCR7 and CD45RO. The percentage of T_naïve (CCR7⁺CD45RO⁻), T_CM (CCR7⁺CD45RO⁺), T_EM (CCR7^-CD45RO⁺), and T_EMRA (CCR7⁻CD45RO⁻) in the peripheral blood of HC and active MPO-AAV patients is shown (n MPO-AAV=33, HC=20). C, D Percentages of CCR6⁺ T cells, CCR4⁺ T cells CXCR3⁺ T cells in the T_EM (CCR7⁻CD45RO⁺), and T_EMRA (CCR7⁻CD45RO⁻) subpopulation were shown