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Table 2 Patients’ clinical and biological features at time of blood sampling

From: Altered circulating CCR6+and CXCR3+ T cell subsets are associated with poor renal prognosis in MPO-ANCA-associated vasculitis

  Active MPO-AAV HC
n 33 20
Age (Y), mean (range) 63 (50–82) 59 (33–79)
Gender (F/M) 16/17 11/9
MPO-ANCA titer (median, range) 87.44 (28.48–164.5)  
BVAS (mean, range) 19(15–27)  
White blood cells (109/l) (mean, SD) 7.52±3.05  
Hemoglobin (g/l) (mean, SD) 71.82±16.84  
Platelet (109/l) (mean, SD) 240.58±68.26  
Neutrophil (109/l) (mean, SD) 5.65±2.87  
Neutrophil percentage (%) (mean, SD) 73.67±10.43  
Lymphocyte (109/l) (mean, SD) 1.08±0.65  
Lymphocyte percentage (%) (mean, SD) 15.71±8.88  
CRP (mg/L) (median range) 37.2 (1.45–253)  
ESR (mm/h) (median range) 95 (2–120)  
Clinical manifestation, n (%)
 ENT 2 (6%)  
 Eyes 2 (6%)  
 Pulmonary 31 (94%)  
 Gastrointestinal 17 (52%)  
 Nervous system 1 (3%)  
Renal 33 (100%)  
 Proteinuria, n (%) 31 (94%)  
 Proteinuria(g/day) (median range) 1.6 (0.48–6.87)  
 Heterogeneous hematuria, n (%) 30 (97%)  
 Renal insufficiency, n (%) 33 (100%)  
 Serum creatine(umol/L) (median range) 628 (124–1395)  
 eGFR (ml/min*1.73 m2) (median range) 6.3 (2.3–58)  
Renal pathological data
 Subjects, no. 14  
Classification, n%
 Focal 1 (7.1%)  
 Mixed 2 (14.3%)  
 Crescentic 8 (57.1%)  
 Sclerotic 3 (21.4%)