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Table 1 Characteristics of patients with different hypertensive severity

From: Clinical characteristics, imaging phenotypes and events free survival in Takayasu arteritis patients with hypertension

 

Mild

Moderate

Severe

P- value

Baseline assessment

N = 48

N = 62

N = 94

 

Demography

    

 Female (n, %)

35 (72.9%)

47 (75.8%)

71 (75.5%)

0.752

 Age (years, IQR)

40 (27–49)

35 (27–46)

37 (24–48)

0.271

 Disease duration (months, IQR)

24 (2–96)

34 (6–96)

24 (3–102)

0.513

Clinical manifestation (n, %)

    

 Systemic symptoms (fever, weakness, etc.)

19 (39.6%)

24 (38.7%)

34 (36.2%)

0.924

 Neurological symptoms (headache, amaurosis, etc.)

14 (29.2%)

26 (41.9%)

55 (58.5%)

0.544

 Cardiovascular symptoms (chest distress/pain, etc.)

9 (18.8%)

16 (25.8%)

32 (34.1%)

0.273

Complications (n, %)

    

 Renal insufficiency

2 (4.2%) #, *

5 (8.1%)

11 (11.7%)

0.048

 Heart failure

4 (8.3%)

7 (11.3%)

13 (13.8%)

0.701

 Cerebral infarction

2 (4.2%)

2 (3.2%)

5 (5.3%)

0.821

Artery involvement (n, %)

    

 Abdominal aorta

20 (41.7%)

32 (51.6%)

53 (56.4%)

0.293

 Renal artery

20 (41.7%)*

28 (45.2%)&

68 (72.3%)

0.043

 Thoracic aorta

10 (20.8%)

22 (35.5%)

32 (34.1%)

0.293

 Carotid artery

13 (27.1%)

26 (41.9%)

39 (41.5%)

0.115

 Subclavian artery

27 (52.1%)

33 (53.2%)

47 (50.0%)

0.744

Echocardiography (n, %)

    

 Severe AR

3 (6.3%)

5 (8.1%)

11 (11.7%)

0.082

Follow-up assessment

N = 43

N = 57

N = 87

 

Blood pressure control status (n, %)

    

 Controlled

26 (60.5%)

32 (56.1%)

37 (42.5%)

0.082

 Improved

15 (34.9%)

22 (38.6%)

39 (44.8%)

0.727

 Failure

2 (4.6%)*

3 (5.3%)&

11 (12.6%)

< 0.001

Events (n, %)

    

 Persistent refractory or malignant hypertension

3 (6.9%) #, *

8 (14.0%)

16 (18.4%)

0.016

 Renal insufficiency

2 (4.7%)

4 (7.0%)

6 (6.9%)

0.322

 Congestive heart failure

2 (4.7%)

3 (5.3%)

2 (2.3%)

0.069

Events free survival by the end

81.4%*

70.2%

59.8%

0.047

  1. AR aortic regurgitation; P value: comparison among patients with different hypertensive severity; #p < 0.05 for comparisons between patients with mild and moderate hypertension; *p < 0.05 for comparisons between patients with mild and severe hypertension; &p < 0.05 for comparisons between patients with between patients with moderate and severe hypertension