Skip to main content

Table 1 Characteristics of patients with different hypertensive severity

From: Clinical characteristics, imaging phenotypes and events free survival in Takayasu arteritis patients with hypertension

  Mild Moderate Severe P- value
Baseline assessment N = 48 N = 62 N = 94  
Demography     
 Female (n, %) 35 (72.9%) 47 (75.8%) 71 (75.5%) 0.752
 Age (years, IQR) 40 (27–49) 35 (27–46) 37 (24–48) 0.271
 Disease duration (months, IQR) 24 (2–96) 34 (6–96) 24 (3–102) 0.513
Clinical manifestation (n, %)     
 Systemic symptoms (fever, weakness, etc.) 19 (39.6%) 24 (38.7%) 34 (36.2%) 0.924
 Neurological symptoms (headache, amaurosis, etc.) 14 (29.2%) 26 (41.9%) 55 (58.5%) 0.544
 Cardiovascular symptoms (chest distress/pain, etc.) 9 (18.8%) 16 (25.8%) 32 (34.1%) 0.273
Complications (n, %)     
 Renal insufficiency 2 (4.2%) #, * 5 (8.1%) 11 (11.7%) 0.048
 Heart failure 4 (8.3%) 7 (11.3%) 13 (13.8%) 0.701
 Cerebral infarction 2 (4.2%) 2 (3.2%) 5 (5.3%) 0.821
Artery involvement (n, %)     
 Abdominal aorta 20 (41.7%) 32 (51.6%) 53 (56.4%) 0.293
 Renal artery 20 (41.7%)* 28 (45.2%)& 68 (72.3%) 0.043
 Thoracic aorta 10 (20.8%) 22 (35.5%) 32 (34.1%) 0.293
 Carotid artery 13 (27.1%) 26 (41.9%) 39 (41.5%) 0.115
 Subclavian artery 27 (52.1%) 33 (53.2%) 47 (50.0%) 0.744
Echocardiography (n, %)     
 Severe AR 3 (6.3%) 5 (8.1%) 11 (11.7%) 0.082
Follow-up assessment N = 43 N = 57 N = 87  
Blood pressure control status (n, %)     
 Controlled 26 (60.5%) 32 (56.1%) 37 (42.5%) 0.082
 Improved 15 (34.9%) 22 (38.6%) 39 (44.8%) 0.727
 Failure 2 (4.6%)* 3 (5.3%)& 11 (12.6%) < 0.001
Events (n, %)     
 Persistent refractory or malignant hypertension 3 (6.9%) #, * 8 (14.0%) 16 (18.4%) 0.016
 Renal insufficiency 2 (4.7%) 4 (7.0%) 6 (6.9%) 0.322
 Congestive heart failure 2 (4.7%) 3 (5.3%) 2 (2.3%) 0.069
Events free survival by the end 81.4%* 70.2% 59.8% 0.047
  1. AR aortic regurgitation; P value: comparison among patients with different hypertensive severity; #p < 0.05 for comparisons between patients with mild and moderate hypertension; *p < 0.05 for comparisons between patients with mild and severe hypertension; &p < 0.05 for comparisons between patients with between patients with moderate and severe hypertension