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Table 4 Multivariate Cox regression analysis of risk factors associated with events free survival during the follow-up

From: Clinical characteristics, imaging phenotypes and events free survival in Takayasu arteritis patients with hypertension

 

HR

95% CI

P -value

Baseline complications

   

 Renal insufficiency

0.84

0.77–3.18

0.167

 Heart dysfunction

0.89

0.81–4.13

0.241

 Cerebrovascular events

0.96

0.79–2.14

0.383

 Co-exist with severe AR

0.87

0.64–0.95

0.043

Imaging phenotype

   

 Cluster 1 imaging phenotype

0.69

0.48–0.92

0.017

 Cluster 2 imaging phenotype

1.27

0.77–4.21

0.441

 Cluster 3 imaging phenotype

0.72

0.43–0.94

0.048

Baseline hypertensive severity

   

 Mild

1.79

0.78–1.32

0.108

 Moderate

1.03

0.82–2.11

0.094

 Severe

0.87

0.63–3.18

0.069

Blood pressure control status

   

 Controlled

2.13

1.32–3.78

0.047

 Improved

1.97

0.89–2.31

0.136

 Failure

0.74

0.68–1.32

0.087

Cluster 1+ controlled blood pressure

1 (reference)

  

 Cluster 1+ uncontrolled blood pressure

0.64

0.52–0.89

0.031

 Cluster 2+ controlled blood pressure

2.21

1.47–4.32

0.027

 Cluster 2+ uncontrolled blood pressure

1.48

0.89–3.11

0.074

 Cluster 3+ controlled blood pressure

1.13

0.91–2.33

0.069

 Cluster 3+ uncontrolled blood pressure

0.83

0.76–0.92

0.048

  1. Cluster 1: involvement of abdominal aorta and/or renal artery; Cluster 2: involvement of ascending aorta, thoracic aorta, aortic arch, and its branches; Cluster 3: involvement of Cluster 1 plus Cluster 2; AR: aortic regurgitation; adjustment: age, sex, disease duration, as well as disease activity and treatment including medication and revascularization procedure; uncontrolled blood pressure: improved and failure blood pressure control status