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Table 4 Multivariate Cox regression analysis of risk factors associated with events free survival during the follow-up

From: Clinical characteristics, imaging phenotypes and events free survival in Takayasu arteritis patients with hypertension

  HR 95% CI P -value
Baseline complications    
 Renal insufficiency 0.84 0.77–3.18 0.167
 Heart dysfunction 0.89 0.81–4.13 0.241
 Cerebrovascular events 0.96 0.79–2.14 0.383
 Co-exist with severe AR 0.87 0.64–0.95 0.043
Imaging phenotype    
 Cluster 1 imaging phenotype 0.69 0.48–0.92 0.017
 Cluster 2 imaging phenotype 1.27 0.77–4.21 0.441
 Cluster 3 imaging phenotype 0.72 0.43–0.94 0.048
Baseline hypertensive severity    
 Mild 1.79 0.78–1.32 0.108
 Moderate 1.03 0.82–2.11 0.094
 Severe 0.87 0.63–3.18 0.069
Blood pressure control status    
 Controlled 2.13 1.32–3.78 0.047
 Improved 1.97 0.89–2.31 0.136
 Failure 0.74 0.68–1.32 0.087
Cluster 1+ controlled blood pressure 1 (reference)   
 Cluster 1+ uncontrolled blood pressure 0.64 0.52–0.89 0.031
 Cluster 2+ controlled blood pressure 2.21 1.47–4.32 0.027
 Cluster 2+ uncontrolled blood pressure 1.48 0.89–3.11 0.074
 Cluster 3+ controlled blood pressure 1.13 0.91–2.33 0.069
 Cluster 3+ uncontrolled blood pressure 0.83 0.76–0.92 0.048
  1. Cluster 1: involvement of abdominal aorta and/or renal artery; Cluster 2: involvement of ascending aorta, thoracic aorta, aortic arch, and its branches; Cluster 3: involvement of Cluster 1 plus Cluster 2; AR: aortic regurgitation; adjustment: age, sex, disease duration, as well as disease activity and treatment including medication and revascularization procedure; uncontrolled blood pressure: improved and failure blood pressure control status