Fig. 3
From: Urate-induced epigenetic modifications in myeloid cells
Methyltransferase inhibition limits gout inflammation in mice. Macroscopic (A) scores of the knees in mice treated with vehicle control or oxonic acid + urate in the presence or absence of methyl transferase inhibitor MTA (methyl-thio-adenosine) followed by intraarticular injection of MSU+C16:0. Inflammation was scored at 24 h. Histology (H&E staining) of joints treated with MSU+C16:0 in oxonic acid + urate mice (B) and in the presence of MTA (C)