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Table 4 Multinomial logistic regression models of baseline variables associated with being in a SR or RR latent class adjusted for age, gender, disease duration and time in the study

From: Distinct patterns of disease activity over time in patients with active SLE revealed using latent class trajectory models

 

Slow responder (SR)

Rapid responder (RR)

 

OR

95% CI

P

OR

95% CI

P

Baseline nBILAG-2004 score

1.100

1.067, 1.132

<0.001

1.089

1.060 1.119

<0.001

BILAG A or B constitutional

3.072

1.576, 5.990

0.001

4.196

2.323, 7.580

<0.001

BILAG A or B musculoskeletal

2.252

1.150, 4,410

0.018

3.073

1.692, 5.580

<0.001

BILAG A or B cardiorespiratory

1.607

0.894, 2.887

0.113

2.461

1.510, 4.011

<0.001

Medication

      

Study arm

      

 Placebo

Ref

Ref

Ref

Ref

Ref

Ref

 E-mab 1200mg QoW

1.344

0.904, 2.000

0.144

1.417

1.017, 1.975

0.039

 E-mab 600mg QW

1.379

0.934, 1.036

0.106

1.237

0.887, 1.726

0.209

Baseline steroid dose (mg/day)

1.028

1.008, 1.049

0.005

1.033

1.016, 1.051

<0.001