Author | Number of patients | Aim of study | Comparison with other diagnostic modality | Feasibility | Cutoff value of B-line number | Sensitivity (%) | Specificity (%) | NPV (%) | PPV (%) | AUC (%) |
---|---|---|---|---|---|---|---|---|---|---|
Moazedi-Fuerst et al. [55] | 64 RA patients | To screen subclinical RA-ILD | HRCT | N/A | N/A | 97.1 | 97.3 | 98.6 | 94.3 | N/A |
Barskova et al. [56] | 58 SSc patients, including 32 VEDOSS | To screen early SSc-ILD | HRCT | 100% | > 5 ≥20 | 100 83 | 55 96 | 100 N/A | 78 N/A | 94 N/A |
Gutiérrez et al. [57] | 133 SSc patients | To detect and predict asymptomatic SSc-ILD | HRCT | N/A | N/A | 91.2% | 88.6% | N/A | N/A | N/A |
Çakir et al. [58] | 48 SSc patients | To evaluate the severity of SSc-ILD | HRCT | N/A | ≥6 > 24 | 100 79.3 | 84.2 94.7 | 100 N/A | 90.6 N/A | 93.7 94.8 |
Vizioli et al. [37] | 104 suspected ILD patients | To evaluate the accuracy of LUS detection of ILD | HRCT | 100% | > 5 > 10 | 92 92 | 53 66 | 87 90 | 64 71 | 90 N/A |
Aghdashi et al. [59] | 31 suspected rheumatoid lung involvement patients | To investigate the utility of LUS | HRCT | N/A | > 5 | 73.5 | 88.2 | 51.7 | 95.1 | N/A |