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Table 1 Baseline WPAI scores: RAJ3

From: Patient- and physician-reported outcomes from two phase 3 randomized studies (RAJ3 and RAJ4) of peficitinib (ASP015K) in Asian patients with rheumatoid arthritis

WPAI domaina Placebo (N=101) Peficitinib 100 mg (N=104) Peficitinib 150 mg (N=102) Peficitinib 100 mg + 150 mg (N=206) p valueb
Absenteeismc
n 50 60 53 113 0.385
 Mean (SD) 4.29 (11.10) 7.61 (22.79) 9.52 (21.17) 8.50 (21.97)
Presenteeismc
n 50 57 53 110 0.639
 Mean (SD) 47.00 (28.94) 41.58 (28.83) 44.53 (31.04) 43.00 (29.82)
Loss of work productivityc
n 50 57 53 110 0.529
 Mean (SD) 48.89 (28.89) 42.57 (29.46) 47.19 (31.85) 44.80 (30.58)
Daily activity impairment
n 100 103 102 205 0.543
 Mean (SD) 55.90 (28.92) 51.75 (28.26) 55.20 (28.97) 53.46 (28.60)
  1. SD Standard deviation, WPAI Work Productivity and Activity Impairment
  2. aHigher WPAI scores indicate greater work/activity impairment, expressed as percentage
  3. bp values calculated using analysis of covariance, with no adjustment made for multiplicity
  4. cOnly “full-time paid workers” and “part-time paid workers” were included (not “homemakers”)