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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis

Fig. 3

Prevention of bleomycin-induced lung fibrosis using PPAR agonist lanifibranor in TβRII∆k-fib mice. A Histogram showing mean Ashcroft score across 12 treatment groups; with detailed mean (n) data table below; n = 4–8 per group. B Representative H&E × 10 sections of the main comparator groups, arrow delineates area of severe continued fibrosis in TG animal in vehicle group following bleomycin, not present in other groups. C Confirmatory Sircol™ assay data for 12 comparator groups (n = 3–10 per group)

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