|
Overall
|
Seropositive
|
Elevated CRP
|
---|
| |
No
|
Yes
|
P value
|
No
|
Yes
|
P value
|
---|
N
|
870
|
827
|
43
| |
748
|
122
| |
Sex = female
|
666 (76.6)
|
632 (76.4)
|
34 (79.1)
|
0.83
|
564 (75.4)
|
102 (83.6)
|
0.062
|
Age (mean (SDb))
|
51.78 (12.1)
|
51.57 (12.1)
|
55.67 (10.6)
|
0.03
|
51.72 (12.1)
|
52.12 (11.9)
|
0.741
|
BMIb category
| | | |
0.727
| | |
< 0.001
|
Underweight
|
14 ( 1.7)
|
14 ( 1.7)
|
0 ( 0.0)
| |
13 ( 1.8)
|
1 ( 0.9)
| |
Normal weight
|
374 (44.2)
|
357 (44.4)
|
17 (40.5)
| |
349 (47.9)
|
25 (21.4)
| |
Overweight
|
293 (34.6)
|
276 (34.3)
|
17 (40.5)
| |
258 (35.4)
|
35 (29.9)
| |
Obese
|
165 (19.5)
|
157 (19.5)
|
8 (19.0)
| |
109 (15.0)
|
56 (47.9)
| |
Age left education
| | | |
0.836
| | |
0.035
|
Less than 16 years
|
51 ( 6.0)
|
49 ( 6.0)
|
2 ( 4.8)
| |
43 ( 5.8)
|
8 ( 6.7)
| |
16–17 years
|
333 (38.9)
|
319 (39.1)
|
14 (33.3)
| |
278 (37.7)
|
55 (46.2)
| |
18–20 years
|
209 (24.4)
|
198 (24.3)
|
11 (26.2)
| |
176 (23.8)
|
33 (27.7)
| |
21+ years
|
264 (30.8)
|
249 (30.6)
|
15 (35.7)
| |
241 (32.7)
|
23 (19.3)
| |
Smoking status
| | | |
0.729
| | |
0.08
|
Never smoker
|
498 (57.3)
|
471 (57.0)
|
27 (62.8)
| |
439 (58.8)
|
59 (48.4)
| |
Former smoker
|
315 (36.2)
|
301 (36.4)
|
14 (32.6)
| |
260 (34.8)
|
55 (45.1)
| |
Current smoker
|
56 ( 6.4)
|
54 ( 6.5)
|
2 ( 4.7)
| |
48 ( 6.4)
|
8 ( 6.6)
| |
Ethnicity
| | | |
0.001
| | |
0.094
|
White
|
851 (97.9)
|
811 (98.2)
|
40 (93.0)
| |
734 (98.3)
|
117 (95.9)
| |
Mixed
|
4 ( 0.5)
|
4 ( 0.5)
|
0 ( 0.0)
| |
4 ( 0.5)
|
0 ( 0.0)
| |
Asian
|
8 ( 0.9)
|
5 ( 0.6)
|
3 ( 7.0)
| |
6 ( 0.8)
|
2 ( 1.6)
| |
Black
|
4 ( 0.5)
|
4 ( 0.5)
|
0 ( 0.0)
| |
2 ( 0.3)
|
2 ( 1.6)
| |
Chinese
|
2 ( 0.2)
|
2 ( 0.2)
|
0 ( 0.0)
| |
1 ( 0.1)
|
1 ( 0.8)
| |
Average units of alcohol per week (mean (SDb))
|
7.44 (8.83)
|
7.40 (8.76)
|
8.21 (10.20)
|
0.559
|
7.53 (8.94)
|
6.90 (8.14)
|
0.472
|
Diabetes mellitus
|
28 ( 3.2)
|
23 ( 2.8)
|
5 (11.9)
|
0.005
|
20 ( 2.7)
|
8 ( 6.6)
|
0.048
|
Psoriasis
|
38 ( 4.4)
|
37 ( 4.5)
|
1 ( 2.4)
|
0.789
|
30 ( 4.0)
|
8 ( 6.6)
|
0.298
|
Hypertension
|
134 (15.5)
|
126 (15.3)
|
8 (18.6)
|
0.714
|
104 (14.0)
|
30 (24.8)
|
0.003
|
Depression
|
169 (19.7)
|
164 (20.1)
|
5 (11.6)
|
0.245
|
138 (18.6)
|
31 (26.3)
|
0.068
|
IMDb quintile
| | | |
0.587
| | |
0.749
|
1 (most deprived)
|
64 ( 7.9)
|
61 ( 7.9)
|
3 ( 7.5)
| |
56 ( 8.0)
|
8 ( 6.8)
| |
2
|
133 (16.3)
|
126 (16.3)
|
7 (17.5)
| |
109 (15.6)
|
24 (20.5)
| |
3
|
186 (22.8)
|
181 (23.4)
|
5 (12.5)
| |
160 (22.9)
|
26 (22.2)
| |
4
|
212 (26.0)
|
199 (25.7)
|
13 (32.5)
| |
182 (26.1)
|
30 (25.6)
| |
5 (least deprived)
|
220 (27.0)
|
208 (26.8)
|
12 (30.0)
| |
191 (27.4)
|
29 (24.8)
| |
- aData are shown as number (percentage) unless otherwise indicated. bSD, standard deviation; BMI, body mass index; IMD, Index of Multiple Deprivation