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Table 1 Characteristics of cohort overall and stratified by seropositivity and elevated CRP (N = 870)a

From: Symptoms in first-degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) questionnaire in the PRe-clinical EValuation of Novel Targets in RA (PREVeNT-RA) Cohort

 

Overall

Seropositive

Elevated CRP

  

No

Yes

P value

No

Yes

P value

N

870

827

43

 

748

122

 

Sex = female

666 (76.6)

632 (76.4)

34 (79.1)

0.83

564 (75.4)

102 (83.6)

0.062

Age (mean (SDb))

51.78 (12.1)

51.57 (12.1)

55.67 (10.6)

0.03

51.72 (12.1)

52.12 (11.9)

0.741

BMIb category

   

0.727

  

< 0.001

 Underweight

14 ( 1.7)

14 ( 1.7)

0 ( 0.0)

 

13 ( 1.8)

1 ( 0.9)

 

 Normal weight

374 (44.2)

357 (44.4)

17 (40.5)

 

349 (47.9)

25 (21.4)

 

 Overweight

293 (34.6)

276 (34.3)

17 (40.5)

 

258 (35.4)

35 (29.9)

 

 Obese

165 (19.5)

157 (19.5)

8 (19.0)

 

109 (15.0)

56 (47.9)

 

Age left education

   

0.836

  

0.035

 Less than 16 years

51 ( 6.0)

49 ( 6.0)

2 ( 4.8)

 

43 ( 5.8)

8 ( 6.7)

 

 16–17 years

333 (38.9)

319 (39.1)

14 (33.3)

 

278 (37.7)

55 (46.2)

 

 18–20 years

209 (24.4)

198 (24.3)

11 (26.2)

 

176 (23.8)

33 (27.7)

 

 21+ years

264 (30.8)

249 (30.6)

15 (35.7)

 

241 (32.7)

23 (19.3)

 

Smoking status

   

0.729

  

0.08

 Never smoker

498 (57.3)

471 (57.0)

27 (62.8)

 

439 (58.8)

59 (48.4)

 

 Former smoker

315 (36.2)

301 (36.4)

14 (32.6)

 

260 (34.8)

55 (45.1)

 

 Current smoker

56 ( 6.4)

54 ( 6.5)

2 ( 4.7)

 

48 ( 6.4)

8 ( 6.6)

 

Ethnicity

   

0.001

  

0.094

 White

851 (97.9)

811 (98.2)

40 (93.0)

 

734 (98.3)

117 (95.9)

 

 Mixed

4 ( 0.5)

4 ( 0.5)

0 ( 0.0)

 

4 ( 0.5)

0 ( 0.0)

 

 Asian

8 ( 0.9)

5 ( 0.6)

3 ( 7.0)

 

6 ( 0.8)

2 ( 1.6)

 

 Black

4 ( 0.5)

4 ( 0.5)

0 ( 0.0)

 

2 ( 0.3)

2 ( 1.6)

 

 Chinese

2 ( 0.2)

2 ( 0.2)

0 ( 0.0)

 

1 ( 0.1)

1 ( 0.8)

 

Average units of alcohol per week (mean (SDb))

7.44 (8.83)

7.40 (8.76)

8.21 (10.20)

0.559

7.53 (8.94)

6.90 (8.14)

0.472

Diabetes mellitus

28 ( 3.2)

23 ( 2.8)

5 (11.9)

0.005

20 ( 2.7)

8 ( 6.6)

0.048

Psoriasis

38 ( 4.4)

37 ( 4.5)

1 ( 2.4)

0.789

30 ( 4.0)

8 ( 6.6)

0.298

Hypertension

134 (15.5)

126 (15.3)

8 (18.6)

0.714

104 (14.0)

30 (24.8)

0.003

Depression

169 (19.7)

164 (20.1)

5 (11.6)

0.245

138 (18.6)

31 (26.3)

0.068

IMDb quintile

   

0.587

  

0.749

 1 (most deprived)

64 ( 7.9)

61 ( 7.9)

3 ( 7.5)

 

56 ( 8.0)

8 ( 6.8)

 

 2

133 (16.3)

126 (16.3)

7 (17.5)

 

109 (15.6)

24 (20.5)

 

 3

186 (22.8)

181 (23.4)

5 (12.5)

 

160 (22.9)

26 (22.2)

 

 4

212 (26.0)

199 (25.7)

13 (32.5)

 

182 (26.1)

30 (25.6)

 

 5 (least deprived)

220 (27.0)

208 (26.8)

12 (30.0)

 

191 (27.4)

29 (24.8)

 
  1. aData are shown as number (percentage) unless otherwise indicated. bSD, standard deviation; BMI, body mass index; IMD, Index of Multiple Deprivation
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Arthritis Research & Therapy

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