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Table 4 Symptoms and associations with symmetrical and small joint pain (N = 829)

From: Symptoms in first-degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) questionnaire in the PRe-clinical EValuation of Novel Targets in RA (PREVeNT-RA) Cohort

Symptom present Number without symmetrical and small joint pain (%) Number with small and symmetrical joint pain (%) Univariate logistic regression odds ratio (95% CI)$ Multivariatea logistic regression odds ratio (95% confidence interval)b
Joint pain 51 (7.5) 53 (36.8) 7.2 (4.7, 11.3) 2.16 (1.15, 4.09)
Joint swell 84 (10.8) 20 (41.7) 5.9 (3.2, 11.0) 1.03 (0.40, 2.64)
Joint stiff 59 (8.0) 45 (48.4) 10.8 (6.6, 17.5) 3.00 (1.50, 6.00)
Joint burn 88 (11.0) 16 (57.1) 10.8 (4.9, 23.6) 2.91 (1.03, 8.24)
Joint tingling 85 (10.6) 19 (73.1) 22.9 (9.4, 56.1) 7.32 (2.49, 21.49)
Colour 100 (12.3) 4 (28.6) 2.9 (0.9, 9.3) 0.52 (0.10, 2.84)
Cramp 78 (10.6) 26 (28.9) 3.4 (2.1, 5.7) 1.47 (0.75, 2.88)
Weakness 73 (9.7) 31 (42.5) 6.9 (4.1, 11.7) 1.28 (0.61, 2.70)
Fatigue 56 (8.1) 48 (34.5) 6.0 (3.8, 9.3) 2.03 (1.06, 3.89)
Distress 69 (9.9) 35 (6.5) 3.3 (2.1, 5.2) 0.89 (0.44, 1.79)
Concentration difficulties 80 (10.4) 24 (39.3) 5.6 (3.2, 9.8) 0.88 (0.36, 2.15)
Sleep disturbances 58 (8.8) 46 (27.2) 3.9 (2.5, 6.0) 1.31 (0.71, 2.42)
  1. aAll symptoms modelled together, with no other adjustment. b Odds ratio is considered significantly different from one if the 95% CI does not include one