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Table 4 TBT on radiographs in KOA: what is already known

From: Trabecular bone texture analysis of conventional radiographs in the assessment of knee osteoarthritis: review and viewpoint

N°

What is already known

1

TBT changes constitute one of the integral features of OA initiation and progression

2

TBT phenotype of patients with progressive OA is associated with apparent thickening of horizontal trabeculae and thinning of vertical trabeculae

3

TBT parameters evaluated from 2D radiographs reflect the subchondral trabecular bone 3D microarchitecture assessed by CT

4

Using TBT parameters in OA trials does not require supplementary methods for cross-calibration of devices at different clinical centers in addition to the standardized radiographic data acquisition procedures already performed in phase III trials