Accelerated osteoarthritis in women with polycystic ovary syndrome: a prospective nationwide registry-based cohort study

Table 1 Characteristics of PCOS patients and controls

		PCOS		Controls
		N = 18,923		N = 56,166
		N	%	N	%	p value
Age (years) at first diagnosis, median (Q1–Q3)		29 (24–36)		29 (24-36)		0.523
< 30 years		9592 (51%)		28,621 (51%)		0.985
30 to < 35 years		3756 (20%)		11,160 (20%)
35 to < 40 years		2497 (13%)		7394 (13%)
40 to < 45 years		1366 (7%)		4023 (7%)
45 to < 50 years		848 (4%)		2476 (4%)
50 to < 55 years		515 (3%)		1496 (3%)
55 to < 60 years		349 (2%)		996 (2%)
Comorbidity (Charlson index ≥1)		1204	6.36	2.236	3.98	< 0.001
Cardiometabolic diseases	ICD-10 codes
Obesity	E66	2263	11.96	759	1.35	< 0.001
Diabetes	E10 to E14	414	2.19	407	0.72	< 0.001
Type 1 diabetes	E10	159	0.84	298	0.53	< 0.001
Type 2 diabetes	E11	294	1.55	167	0.30	< 0.001
Gestational diabetes	O24, P70	285	1.51	211	0.38	< 0.001
Dyslipidaemia	E78	101	0.53	100	0.18	< 0.001
Hypertension	I109	318	1.68	331	0.59	< 0.001
Cardiovascular disease	I20, I50	67	0.35	161	0.29	0.145
Myocardial infarction	I21 to I25	34	0.18	114	0.20	0.532
Transient cerebral ischemia	G45	25	0.13	46	0.08	0.052
Stroke	I63, I64	45	0.24	75	0.23	0.002
Thrombosis, lung embolism	I26, O082, I80 to I82	121	0.64	168	0.30	< 0.001

ISSN: 1478-6362