| | |
PCOS
|
Controls
| |
|---|
| | |
N = 18,923
|
N = 56,166
| |
|---|
| | |
N
|
%
|
N
|
%
|
p value
|
|---|
|
Age (years) at first diagnosis, median (Q1–Q3)
|
29 (24–36)
|
29 (24-36)
|
0.523
|
|
< 30 years
|
9592 (51%)
|
28,621 (51%)
|
0.985
|
|
30 to < 35 years
|
3756 (20%)
|
11,160 (20%)
| |
|
35 to < 40 years
|
2497 (13%)
|
7394 (13%)
| |
|
40 to < 45 years
|
1366 (7%)
|
4023 (7%)
| |
|
45 to < 50 years
|
848 (4%)
|
2476 (4%)
| |
|
50 to < 55 years
|
515 (3%)
|
1496 (3%)
| |
|
55 to < 60 years
|
349 (2%)
|
996 (2%)
| |
|
Comorbidity (Charlson index ≥1)
|
1204
|
6.36
|
2.236
|
3.98
|
< 0.001
|
|
Cardiometabolic diseases
|
ICD-10 codes
| | | | | |
|
Obesity
|
E66
|
2263
|
11.96
|
759
|
1.35
|
< 0.001
|
|
Diabetes
|
E10 to E14
|
414
|
2.19
|
407
|
0.72
|
< 0.001
|
|
Type 1 diabetes
|
E10
|
159
|
0.84
|
298
|
0.53
|
< 0.001
|
|
Type 2 diabetes
|
E11
|
294
|
1.55
|
167
|
0.30
|
< 0.001
|
|
Gestational diabetes
|
O24, P70
|
285
|
1.51
|
211
|
0.38
|
< 0.001
|
|
Dyslipidaemia
|
E78
|
101
|
0.53
|
100
|
0.18
|
< 0.001
|
|
Hypertension
|
I109
|
318
|
1.68
|
331
|
0.59
|
< 0.001
|
|
Cardiovascular disease
|
I20, I50
|
67
|
0.35
|
161
|
0.29
|
0.145
|
|
Myocardial infarction
|
I21 to I25
|
34
|
0.18
|
114
|
0.20
|
0.532
|
|
Transient cerebral ischemia
|
G45
|
25
|
0.13
|
46
|
0.08
|
0.052
|
|
Stroke
|
I63, I64
|
45
|
0.24
|
75
|
0.23
|
0.002
|
|
Thrombosis, lung embolism
|
I26, O082, I80 to I82
|
121
|
0.64
|
168
|
0.30
|
< 0.001
|
- ICD International Classification of Diseases
