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Table 3 Modified Mankin score for evaluation of articular cartilage degeneration as described by Henson and Vincent [32]

From: Comparison of properties determined using electromechanical assessment (Arthro-BST™) with macroscopic and histological properties in symptomatic human articular cartilage of the hip

Score

Structure

Cellularity

Matrix staining

Tidemark integrity

Score 0

Smooth surface

Normal arrangement

Normal staining

Normal and intact

Normal appearance

   

Score 1

Roughened surface

Clustering in the superficial layer or loss of cells up to 10%

Slight loss of stain

Disrupted

Single crack or area of delamination

  

Score 2

Multiple cracks

Disorganization or loss up to 25%

Moderate loss of stain

 

Moderate delamination

  

Score 3

Fragmentation in cartilage or severe delamination

Cell rows absent or loss up to 50%

Severe loss of stain

 

Score 4

Loss of fragments

Very few cells present

No stain present

 

Score 5

Complete erosion to tidemark

   

Score 6

Erosion beyond tidemark