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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Impact of the HLA-DRB1 shared epitope on responses to treatment with tofacitinib or abatacept in patients with rheumatoid arthritis

Fig. 5

Copy numbers of SE alleles and EULAR response criteria. The percentage of patients meeting EULAR responses criteria stratified according to the copy numbers of SE alleles are shown 4, 12, and 24 weeks after the start of treatment with tofacitinib (A) or abatacept (B). The effects of the copy numbers of SE alleles on the percentage of patients who achieved a good EULAR response at 24 weeks in each treatment group was assessed by the Cochran-Armitage test; not significant for tofacitinib, p = 0.0182 for abatacept. EULAR, European League Against Rheumatism; SE 0, 0 copies of shared epitope alleles; SE 1, 1 copy of shared epitope alleles; SE 2, 2 copies of shared epitope alleles

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