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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA

Fig. 2

Change in shape for the anterior femur (top row) and posterior femur (bottom row), for various B-scores. Red indicates where there is an increase in size (locally calculated, based on anatomically corresponded triangles from the shape model), blue indicates decrease in size (locally); scale shows percentage in area size change of each triangle. Change tends to be greatest around the edge of the cartilage plate (osteophyte region), but it also occurs in central subchondral regions where the bone flattens out. Adapted from Bowes et al. [11]

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