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Table 4 Pearson correlations between femur bone shape stabilization and tibiofemoral cartilage thickening/stabilization in TPX-100-treated knee

From: Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA

Change period

Knee compatment

n

Correlation coefficient

p-value

Baseline to 6 months

Entire femoral condyle

78

− 0.206

0.07

Medial femoral condyle

78

− 0.265

0.02

Entire TF

78

− 0.193

0.09

Medial TF

78

− 0.212

0.06

Baseline to 12 months

Entire femoral condyle

78

− 0.303

0.007

Medial femoral condyle

78

− 0.329

0.003

Entire TF

78

− 0.296

0.009

Medial TF

78

– 0.320

0.004