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Table 4 Pearson correlations between femur bone shape stabilization and tibiofemoral cartilage thickening/stabilization in TPX-100-treated knee

From: Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA

Change period Knee compatment n Correlation coefficient p-value
Baseline to 6 months Entire femoral condyle 78 − 0.206 0.07
Medial femoral condyle 78 − 0.265 0.02
Entire TF 78 − 0.193 0.09
Medial TF 78 − 0.212 0.06
Baseline to 12 months Entire femoral condyle 78 − 0.303 0.007
Medial femoral condyle 78 − 0.329 0.003
Entire TF 78 − 0.296 0.009
Medial TF 78 – 0.320 0.004