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Table 5 Pearson correlations between femur bone shape stabilization and tibiofemoral cartilage thickening/stabilization in control knee

From: Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA

Change period

Knee compartment

n

Correlation coefficient

p-value

Baseline to 6 months

Entire femoral condyle

78

− 0.068

0.55

Medial femoral condyle

78

− 0.053

0.65

Entire TF

78

0.043

0.71

Medial TF

78

0.011

0.93

Baseline to 12 months

Entire femoral condyle

78

− 0.174

0.13

Medial femoral condyle

78

− 0.246

0.03

Entire TF

76

0.011

0.92

Medial TF

77

− 0.085

0.46