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Table 5 Pearson correlations between femur bone shape stabilization and tibiofemoral cartilage thickening/stabilization in control knee

From: Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA

Change period Knee compartment n Correlation coefficient p-value
Baseline to 6 months Entire femoral condyle 78 − 0.068 0.55
Medial femoral condyle 78 − 0.053 0.65
Entire TF 78 0.043 0.71
Medial TF 78 0.011 0.93
Baseline to 12 months Entire femoral condyle 78 − 0.174 0.13
Medial femoral condyle 78 − 0.246 0.03
Entire TF 76 0.011 0.92
Medial TF 77 − 0.085 0.46