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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status

Fig. 1

Analysis of major lineages revealed no differences between ACPA+ and ACPA− patients. A Five-level HSNE separated all major lineages as indicated by dashed circles, colour-coded for ACPA status (positive = red, negative = blue). The solid circle indicates innate landmarks. B Examples of expression patterns of the HSNE map shown in A. C Heatmap of clusters identified through default clustering in Cytosplore (Gaussian mean shift) showing the expression pattern. D Manual gating of major lineages showed no significant difference in frequency between ACPA+ and ACPA−

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Arthritis Research & Therapy

ISSN: 1478-6362

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