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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status

Fig. 2

HSNE analysis of all innate subsets indicated differences in basophil and NK cell subsets. A Heatmap representing all clusters within the innate population and their respective expression patterns, cluster 18/24 indicated with black boxes. B Cluster 18 (basophil subset, p = 0.033) was reduced in ACPA− patients and there was a strong trend for cluster 24 (NK cell subset p = 0.063) present only in ACPA− patients (Cytofast). C tSNE plotting samples using clusters 18 and 24 as input confirmed the separation shown in B. D HSNE map indicating cluster 18 and cluster 24 (dashed circles) and examples of the expressed markers. ACPA+ in red, ACPA− in blue

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