Fig. 2From: Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA statusHSNE analysis of all innate subsets indicated differences in basophil and NK cell subsets. A Heatmap representing all clusters within the innate population and their respective expression patterns, cluster 18/24 indicated with black boxes. B Cluster 18 (basophil subset, p = 0.033) was reduced in ACPA− patients and there was a strong trend for cluster 24 (NK cell subset p = 0.063) present only in ACPA− patients (Cytofast). C tSNE plotting samples using clusters 18 and 24 as input confirmed the separation shown in B. D HSNE map indicating cluster 18 and cluster 24 (dashed circles) and examples of the expressed markers. ACPA+ in red, ACPA− in blueBack to article page