Skip to main content

Table 1 Patient clinical characteristics of rheumatoid arthritis patients used in this study

From: Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status

  MC
RA ACPA+
MC
RA ACPA
FC
RA ACPA+
FC
RA ACPA
  n = 8 n = 7 n = 27 n = 20
Age in years, average (range) 64 (48–75) 67 (54–79) 55 (17–81) 51 (21–86)
Females, n (%) 4 (50) 4 (57) 16 (59) 12 (60)
RF positive, n (%) 8 (100) 2 (29) 19(79) 5(21)
Elevated CRP, n (%) 5 (50)a 3 (25) 62(24) 38(15)
SJC, mean (range)b 9 (3–20) 14 (4–29) 5 (0–20) 3 (0–16)
TJC, mean (range)b 11 (2–20) 17 (1–34) 3 (0–16) 3 (0–18)
DMARD usage, n (%)c 0 (0) 0(0) 6 (31%) 4 (36%)
Disease duration (in days), average (range)d 132 (13–600) 42 (21–60) 108 (5–542) 132 (3–610)
  1. aNo CRP was recorded for one male and one female (male ESR = 34, female ESR = 126)
  2. bFor 3 ACPA+ and 2 ACPA−, no SJC/TJC was recorded in the FC dataset
  3. cFor 17 RA patients, no DMARD usage was recorded in the FC dataset, frequency of DMARD calculation based on n = 19 in ACPA+ and n = 11 in ACPA−. DMARD usage included hydroxychloroquine, sulfasalazine and methotrexate
  4. dFor 1 ACPA+ and 1 ACPA−, no disease duration was recorded in the FC dataset
  5. MC mass cytometry, FC flow cytometry, ACPA anti-citrullinated protein antibodies, RF rheumatoid factor, CRP C-reactive protein, SJC swollen joint count, TJC tender joint count, DMARD disease-modifying anti-rheumatic drugs