| Model 1: Clinical factors (n = 252) | Model 2: CTX-I (n = 244) | Model 3: BMD radius (n = 223) | Model 4: CTX-I+ BMD radius (n = 216) | ||||
---|---|---|---|---|---|---|---|---|
Baseline parametersa | β coefficient (SE) | OR (95% CI) | β coefficient (SE) | OR (95% CI) | β coefficient (SE) | OR (95% CI) | β coefficient (SE) | OR (95% CI) |
Age | 0.036 (0.014) | 1.037 (1.010–1.065)** | 0.040 (0.014) | 1.041 (1.012–1.070)** | – | – | – | – |
Hypercholesterolemia | 0.896 (0.381) | 2.450 (1.162–5.164)* | 1.024 (0.393) | 2.784 (1.290–6.010)** | 0.963 (0.390) | 2.621 (1.221–5.624)* | 1.099 (0.404) | 3.002 (1.360–6.626)** |
Smoking: ever and current | 0.611 (0.212) | 1.843 (1.217–2.791)** | 0.649 (0.216) | 1.913 (1.252–2.924)* | 0.903 (0.261) | 2.467 (1.480–4.111)** | 0.988 (0.272) | 2.687 (1.577–4.579)*** |
Presence of carotid plaque | 0.992 (0.288) | 2.697 (1.534–4.739)** | 1.002 (0.295) | 2.723 (1.527–4.853)** | 1.291 (0.282) | 3.637 (2.095–6.316)*** | 1.353 (0.291) | 3.869 (2.190–6.838)*** |
Serum CTX-I (pg/mL) | NA | NA | 1.539 (0.667) | 4.662 (1.262–17.219) | NA | NA | 1.718 (0.731) | 5.574 (1.331–23.341)* |
BMD radius (g/cm2) | NA | NA | NA | NA | –3.057 (1.193) | 0.047 (0.005–0.488)* | –3.667 (1.250) | 0.026 (0.002–0.296)** |
R2 (%) | 24.3 | 27.3 | 25.6 | 29.7 |