From: Impact of systemic lupus erythematosus on the 5-year survival of critically ill septic patients
Univariable | Model-1 | Model-2 | Model-3 | Model-4 | |
---|---|---|---|---|---|
Crude Hrs | Adjusted Hrs | Adjusted Hrs | Adjusted Hrs | Adjusted Hrs | |
SLE (non-SLE as reference) | 2.27 (2.01–2.57) | 2.20 (1.94–2.49) | 2.21 (1.95–2.50) | 2.01 (1.77–2.27) | 1.47 (1.22–1.77) |
Age, (per 1 year increment) | 1.03 (1.02–1.03) | 1.03 (1.02–1.03) | 1.03 (1.02–1.03) | 1.02 (1.01–1.02) | 1.02 (1.02–1.02) |
Gender (male) | 1.38 (1.19–1.61) | 1.24 (1.07–1.45) | 1.23 (1.06–1.44) | 1.14 (0.98–1.33) | 1.11 (0.95–1.30) |
Urbanisation levels | |||||
Urban | Ref. | Ref. | Ref. | Ref. | |
Suburban | 1.01 (0.88–1.17) | 1.06 (0.92–1.22) | 1.09 (0.94–1.25) | 1.11 (0.96–1.28) | |
Rural | 0.97 (0.83–1.14) | 0.89 (0.76–1.05) | 0.92 (0.78–1.07) | 0.94 (0.80–1.11) | |
Low insured incomea | 1.01 (0.90–1.13) | 1.09 (0.97–1.22) | 1.06 (0.95–1.19) | 1.08 (0.97–1.21) | |
CCI > 3 (0-3 as reference) | 3.06 (2.72–3.43) | 2.27 (2.01–2.57) | 2.23 (1.97–2.53) | ||
Recent hospitalised infectionb | 2.04 (1.75–2.38) | 1.35 (1.13–1.60) | 1.33 (1.12–1.59) | ||
Medications | |||||
Glucocorticoid dosage groupc | |||||
0 mg/day | Ref. | Ref. | |||
0-5 mg/day | 1.62 (1.31–2.00) | 1.18 (0.95–1.46) | |||
≥ 5 mg/day | 2.63 (2.17–3.18) | 1.55 (1.27–1.90) | |||
DMARD | |||||
Methotrexate | 2.55 (1.91–3.39) | 2.19 (1.61–2.99) | |||
Sulfasalazine | 1.68 (1.03–2.75) | 0.84 (0.50–1.42) | |||
Hydroxychloroquine | 2.04 (1.78–2.35) | 0.98 (0.80–1.19) | |||
Immunosuppressantsd | 2.14 (1.87–2.45) | 1.45 (1.22–1.74) |