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Table 2 Characteristics of patients reported in selected CNO reference cohorts

From: First-year follow-up of children with chronic nonbacterial osteomyelitis—an analysis of the German National Pediatric Rheumatologic Database from 2009 to 2018

  Canada 2002 [23] USA 2012 [24] France 2015 [25] UK 2016 [10] Germany 2015 [26] Eurofever 2017 [27] Germany NPRD 2020
Number of Patients 23 70 178 41 95 486 774
Male % 17 33 31 25 42 36 37
Female % 83 67 69 75 56 64 63
Mean of age at disease onset 9 9.7 10.9 9 11.7 9.9 11.1
Delay of diagnosis in months 13 6 17 15 11 12 8.4
Number of lesions mean 4 3.5 3 N/A 4 4 3
Unifocal in % 43 29 7 24 16 29 37
Multifocal in % 57 71 93 76 84 71 63
Active disease in % after follow-up 22 39 66 N/A 33 50 47
Months of follow-up 68 22 48 N/A 49 N/A 12
  1. NPRD National Pediatric Rheumatologic Database, N/A not available