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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Expansion of myeloid-derived suppressor cells contributes to metabolic osteoarthritis through subchondral bone remodeling

Fig. 3

High-fat diet (HFD) increases osteoclastogenesis in DMM mice. A Representative images of isolated bone marrow M-MDSC post-M-CSF and RANKL stimulation stained with tartrate-resistant acid phosphatase (TRAP; n = 3 in each group). B Osteoclast number (n = 3 in each group), number of osteoclasts per field of view, each enumeration utilized 5 fields of view/slide at 20×. C Osteoclast nuclei number per osteoclast (n = 3 in each group). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 by two-way ANOVA Tukey’s multiple comparison test

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Arthritis Research & Therapy

ISSN: 1478-6362

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