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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Expansion of myeloid-derived suppressor cells contributes to metabolic osteoarthritis through subchondral bone remodeling

Fig. 4

High-fat diet (HFD) alters subchondral bone parameters with increased osteoclast formation. A Representative histopathological section from mouse subchondral bone stained with tartrate-resistant acid phosphatase (TRAP). B HFD increases osteoclast number in DMM. C Osteoclast area (μm2). D Subchondral bone score. E Subchondral bone thickness. n = 6 in the sham group, n = 5 in the DMM group; scale bar = 100μM. *P < 0.05, ****P < 0.0001 two-way ANOVA Tukey’s multiple comparison test

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Arthritis Research & Therapy

ISSN: 1478-6362

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