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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Lupus susceptibility region containing CTLA4 rs17268364 functionally reduces CTLA4 expression by binding EWSR1 and correlates IFN-α signature

Fig. 2

rs17268364 risk G allele associated with lower expression of CTLA-4. A Integrated analysis of genotype-expression data from HapMap3 individuals including 76 Han Chinese in Beijing, China (CHB), 82 Japanese in Tokyo, Japan (JPT), 90 Yoruba in Ibadan, Nigeria (YRI), 75 Gujarati Indians in Houston, Texas (GIH), 69 Luhya in Webuye, Kenya (LWK), 42 Mexican ancestry in Los Angeles, California (MXL). ILMN_1763487 denotes the probe for CTLA-4 in the gene expression chip (Illumina). B The correlation between mRNA expression of CTLA-4 and rs17268364 genotypes in lupus nephritis patients

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