Skip to main content

Table 1 Association of the rs17268364 with SLE susceptibility

From: Lupus susceptibility region containing CTLA4 rs17268364 functionally reduces CTLA4 expression by binding EWSR1 and correlates IFN-α signature

Cohorts (cases/controls) Population Risk allele (cases/controls) P value OR (95%CI)
Beijing ImmunoChip cohort (490/493) North of China 79.6/74.9 1.41×10−2 1.30(1.06–1.61)
Henan replication cohort (2053/1845) Central of China 78.8/75.5 4.40×10−4 1.21(1.09–1.35)
Beijing replication cohort (2303/19262) North of China 77.8/75.2 1.62×10−4 1.15(1.07–1.24)
Meta-analysisa (4846/21600)    7.02×10−11 1.19(1.13–1.26)
  1. aHeterogeneity I2 = 0%