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Table 1 Association of the rs17268364 with SLE susceptibility

From: Lupus susceptibility region containing CTLA4 rs17268364 functionally reduces CTLA4 expression by binding EWSR1 and correlates IFN-α signature

Cohorts (cases/controls)

Population

Risk allele (cases/controls)

P value

OR (95%CI)

Beijing ImmunoChip cohort (490/493)

North of China

79.6/74.9

1.41×10−2

1.30(1.06–1.61)

Henan replication cohort (2053/1845)

Central of China

78.8/75.5

4.40×10−4

1.21(1.09–1.35)

Beijing replication cohort (2303/19262)

North of China

77.8/75.2

1.62×10−4

1.15(1.07–1.24)

Meta-analysisa (4846/21600)

  

7.02×10−11

1.19(1.13–1.26)

  1. aHeterogeneity I2 = 0%