Cohorts (cases/controls) | Population | Risk allele (cases/controls) | P value | OR (95%CI) |
---|---|---|---|---|
Beijing ImmunoChip cohort (490/493) | North of China | 79.6/74.9 | 1.41×10−2 | 1.30(1.06–1.61) |
Henan replication cohort (2053/1845) | Central of China | 78.8/75.5 | 4.40×10−4 | 1.21(1.09–1.35) |
Beijing replication cohort (2303/19262) | North of China | 77.8/75.2 | 1.62×10−4 | 1.15(1.07–1.24) |
Meta-analysisa (4846/21600) | 7.02×10−11 | 1.19(1.13–1.26) |