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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Unraveling heterogeneity within ACPA-negative rheumatoid arthritis: the subgroup of patients with a strong clinical and serological response to initiation of DMARD treatment favor disease resolution

Fig. 6

Cumulative incidence of SDFR was highest among ACPA-negative RA patients that presented with baseline CRP levels 3 times the ULN in both the study population as the replication population.

Kaplan-Meier curve showing that SDFR is highly prevalent in ACPA-negative RA patients with relatively high baseline CRP levels (≥ 3× ULN) and early DAS remission (DAS4 months < 1.6) in both the study population (A, p = 0.02) and the replication population (B, 0.03). In ACPA-negative RA patients with early DAS remission but baseline CRP levels < 3× ULN, the frequency of SDFR is comparable with ACPA-negative RA patients with DAS4 months ≥ 1.6. BL, baseline; CRP, C-reactive protein; DAS, disease activity score; SDFR, sustained DMARD-free remission

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Arthritis Research & Therapy

ISSN: 1478-6362

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