| Multivariate 5 years | Multivariate 10 years | All mortality |
---|
HR | 95% CI | p | HR | 95% CI | p | HR | 95% CI | p |
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Sex: male | 2.131 | 0.99–4.58 | 0.0526 | 3.42 | 1.75–6.67 | 0.0003 | 3.25 | 1.69–6.22 | 0.0004 |
DLCO <70% | 5.489 | 1.61–18.60 | 0.0063 | 4.54 | 1.74–1.85 | 0.002 | 3.1 | 1.40–6.88 | 0.0053 |
Cardiac involvement | 2.893 | 1.30–6.41 | 0.0089 | 3.18 | 1.62–6.24 | 0.0008 | 2.86 | 1.52–5.41 | 0.0012 |
CRP >5 mg/l | 3.283 | 1.42–7.53 | 0.005 | 2.37 | 1.23–6.460 | 0.01 | 2.13 | 1.14–5.41 | 0.0174 |
- The results are expressed as hazard ratios (HR) with a 95% confidence interval (95% CI), cardiac involvement comprises left ventricle ejection fraction <50%, and/or a TTE anomaly (pericarditis, valvular disease, or diastolic dysfunction), and/or an ECG anomaly (arrhythmia or conduction blocks). PAPs >35 mm Hg and Raynaud’s syndrome appearing after age 45 were not taken into account in the multi-variate analysis given the co-linearities respectively with the DLCO< 70% of the theoretical value and disease onset after the age of 50 years old