Skip to main content

Table 2 Multivariable predictors of mortality in the systemic Scleroderma Toulouse cohort at 5, 10 years, and all mortality

From: Sine scleroderma, limited cutaneous, and diffused cutaneous systemic sclerosis survival and predictors of mortality

 

Multivariate 5 years

Multivariate 10 years

All mortality

HR

95% CI

p

HR

95% CI

p

HR

95% CI

p

Sex: male

2.131

0.99–4.58

0.0526

3.42

1.75–6.67

0.0003

3.25

1.69–6.22

0.0004

DLCO <70%

5.489

1.61–18.60

0.0063

4.54

1.74–1.85

0.002

3.1

1.40–6.88

0.0053

Cardiac involvement

2.893

1.30–6.41

0.0089

3.18

1.62–6.24

0.0008

2.86

1.52–5.41

0.0012

CRP >5 mg/l

3.283

1.42–7.53

0.005

2.37

1.23–6.460

0.01

2.13

1.14–5.41

0.0174

  1. The results are expressed as hazard ratios (HR) with a 95% confidence interval (95% CI), cardiac involvement comprises left ventricle ejection fraction <50%, and/or a TTE anomaly (pericarditis, valvular disease, or diastolic dysfunction), and/or an ECG anomaly (arrhythmia or conduction blocks). PAPs >35 mm Hg and Raynaud’s syndrome appearing after age 45 were not taken into account in the multi-variate analysis given the co-linearities respectively with the DLCO< 70% of the theoretical value and disease onset after the age of 50 years old