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Table 1 Demographic and clinical data of subjects participating to the study

From: Low frequency of disease flare in patients with rheumatic musculoskeletal diseases who received SARS-CoV-2 mRNA vaccine

 

Patients (n=126)

Controls

(n=85)

p

Female:male (% female)

105:19 (84)

62:23 M (72.9)

0.06

Age [median (IQR)], years

51 (17)

49 (20)

0.11

Rheumatoid arthritis, n (%)

31 (24.6)

  

Systemic lupus erythematosus, n (%)

31 (24.6)

  

Psoriatic arthritis, n (%)

26 (20.6)

  

Undifferentiated connective tissue disease, n (%)

11 (8.7)

  

Ankylosing spondylitis, n (%)

9 (7.1)

  

Othera, n (%)

18 (14.3)

  

Glucocorticoids, n (%)

28 (22.2)

  

Hydroxychloroquine, n (%)

30 (23.8)

  

Immunosuppressive drugs

70 (55.6)

  

 Methotrexate, n (%)

21 (16.6)

  

 Other csDMARDs, n (%)

10 (7.9)

  

 TNF inhibitors, n (%)

34 (27)

  

 Other b/tsDMARDs, n (%)

15 (11.9)

  

Stopped ongoing therapy for vaccination, n (%)

28 (22.2)

  
  1. aOther diagnoses included Sjogren syndrome (n=4), scleroderma (n=3), mixed connective tissue diseases (n=2), systemic vasculitis (n=4), and anti-phospholipid syndrome (n=5)
  2. bDMARDs biological disease modifying anti-rheumatic drugs, csDMARDs conventional synthetic disease modifying anti-rheumatic drugs, TNFi tumor necrosis factor inhibitor