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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Involvement of lncRNA IL21-AS1 in interleukin-2 and T follicular regulatory cell activation in systemic lupus erythematosus

Fig. 4

IL21-AS1 is negatively correlated with SLE activity. The relative mRNA expression of IL21-AS1 in isolated PBMCs from patients with SLE (n = 53) was evaluated using qPCR. Correlation between IL21-AS1 expression levels and SLE Disease Activity Index, British Isle Lupus Assessment Group, C3 level, C4 level, CH50 level, C-reactive protein (CRP) level, IgG level, erythrocyte sedimentation rate (ESR), and comparisons of IL21-AS1 levels between patients with SLE classified as positive or negative for anti-double-stranded DNA (anti-dsDNA) antibodies. Anti-dsDNA < 12 denotes a negative test (n = 39). Data symbols represent individual subjects. Spearman’s test was used for the correlation analysis between two variables of interest

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