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Fig. 10 | Arthritis Research & Therapy

Fig. 10

From: Intradiscal injection of monosodium iodoacetate induces intervertebral disc degeneration in an experimental rabbit model

Fig. 10

Histological grading scores. In rabbit intervertebral discs (IVDs) injected with contrast agent (CA) and/or monosodium iodoacetate (MIA) at 2, 4 , 8 , and 12 weeks post-injection, histological grading scores were evaluated using the standardized histopathology scoring system of rabbit IVD degeneration [26,27,28] for the total of seven categories: A total of seven categories, B nucleus pulposus (NP) shape, C NP area, D NP matrix, E NP cellularity, F border between the annulus fibrosus (AF) and NP, G AF, and H endplate. Data are expressed as mean ± standard error of the mean (SEM). The Kruskal-Wallis test was used to compare all groups. *P < 0.05, **P < 0.01

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