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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: CTLA4-Ig treatment induces M1–M2 shift in cultured monocyte-derived macrophages from healthy subjects and rheumatoid arthritis patients

Fig. 2

Protein synthesis of M2 phenotype markers in HS-M1-MDMs treated with CTLA4-Ig. Western blotting and related densitometric analysis of CD163, CD204, CD206, and GAPDH (HK gene) in cultured HS-MDMs maintained in normal growth medium without any stimulation or CTLA4-Ig treatment (white bar), stimulated with LPS alone (HS-M1-MDMs) (light grey bar), or stimulated with LPS and then treated with CTLA4-Ig (abatacept) at a concentration of 100 μg/mL (dark grey bar) and 500 μg/mL (black bar) for 24 and 48 h. The final results were obtained from ten independent in vitro experiments. *p < 0.05

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Arthritis Research & Therapy

ISSN: 1478-6362

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