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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: CTLA4-Ig treatment induces M1–M2 shift in cultured monocyte-derived macrophages from healthy subjects and rheumatoid arthritis patients

Fig. 3

Gene expression of M1 and M2 markers in RA-MDMs treated with CTLA4-Ig. Quantitative real-time PCR of M1 (TLR4, CD80, CD86) or M2 (CD163, CD204, CD206, MerTK) markers in cultured human RA-MDMs maintained in normal growth medium without (white bar) or with CTLA4-Ig (abatacept) treatment at a concentration of 100 μg/mL (dark grey bar) and 500 μg/mL (black bar) for 3 and 12 h. A M1 markers (TLR4, CD80, CD86). A M2 markers (CD163, CD204, CD206, MerTK). The final results were obtained from 7 independent in vitro experiments. *p < 0.05

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Arthritis Research & Therapy

ISSN: 1478-6362

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